Sapient is a fast-growing early-stage biotech company headquartered in San Diego, CA. Our focus is on delivering multi-omics services to accelerate drug development and transform personalized medicine. Combining state-of-the-art mass spectrometry technology with advanced biocomputational services and multifaceted human health data, we enable biomarker discovery at unprecedented speed and scale to provide a deeper understanding of human biology and effectively align biological targets, patients, and drug therapies. We are a highly collaborative team of passionate scientists, clinicians, and engineers with expertise in various disciplines, committed to making innovations with scientific rigor. Ultimately, our platform technology enhances the precision and efficacy of treatments, touching and enhancing countless lives.
We are seeking a highly skilled Senior Scientist to join our Analytical R&D team. The ideal candidate will have a strong background in proteomics and various analytical techniques. If you are passionate about scientific discovery and have a keen eye for detail, we encourage you to apply.
Role and Responsibilities:
- Independently design, evaluate and implement bottom-up and top-down methods for targeted and discovery-based protein measurement in biosamples using DDA and DIA LC-MS workflows.
- Independently deploy non-mass spectrometry-based methodologies for protein enrichment and quantitation including immunoprecipitation and PTM enrichment.
- Ensure data quality through implementation of data monitoring, QC metrics, standardized operating procedures, and formal staff training.
- Maintain LC-MS instrumentation, write standard operating procedures for new methods, and train others on new proteomics protocols for commercial deployment.
- Implement laboratory automation for sample preparation and data analysis pipelines.
- Able to perform and communicate within a collaborative environment with an emphasis on data quality, integrity, and adherence to project deadlines.
Requirements:
- Must have a PhD in Chemistry, chemical engineering, bioengineering, biochemistry, biology, or related scientific field
- A minimum of 5 years postdoctoral and/or professional experience working in proteomics with a focus on, but not limited to, mass-spectrometry-based methods
- Knowledge of FDA regulations and cGMP standards
- Must demonstrate leadership capabilities including coaching and mentoring of junior scientists
- Ability to work in a fast paced client focused environment with a focus on detail and follow up with stakeholders
To apply through our applicant tracking system, please click on the following link:
https://sapientbio.bamboohr.com/careers/36?source=aWQ9MjE%3D
Sapient is an equal opportunity and inclusive employer. We do not discriminate on the basis of race, ethnicity, gender, age, sexual orientation or disability.
Job Type: Full-time
Pay: $170,000.00 - $190,000.00 per year
Benefits:
- 401(k) matching
- Flexible spending account
- Health savings account
- Life insurance
Experience level:
Medical specialties:
Schedule:
- 8 hour shift
- Monday to Friday
Experience:
- Proteomics: 5 years (Required)
- Laboratory experience: 5 years (Required)
Ability to Commute:
- San Diego, CA 92121 (Required)
Ability to Relocate:
- San Diego, CA 92121: Relocate before starting work (Required)
Willingness to travel:
Work Location: In person