Description:
- Support in-house sample analysis, functional characterization and assay development activities.
- Perform routine sample analysis supporting comparability and formulation robustness studies, participant cell-based assay development, optimization, and qualification.
Education & Experience Requirements:
- BS or MS degree in a relevant scientific discipline (no Phd candidates)
- Minimum 3 years experience
Essential Duties:
- Perform cell-based and flow cytometry analysis to support late-stage biologics projects.
- Plans and executes assigned experiments that support assay development activities and project goals.
- Proactively seeks out senior personnel to discuss potential solutions to problems.
- Participates in group meetings to share test results.
- Demonstrates ability to recognize anomalous and inconsistent results and interpret experimental outcomes.
- Develops skills in data analysis and ability to evaluate quality of data.
- Operates scientific equipment, selects appropriate methods and techniques to perform experiments, and prepare related reports.
- Plan and organize details of experiments with guidance.
- Basic understanding of cell-based methods.
- Experience with cell-based assays and flow cytometry analysis and perform routine maintenance of these instruments.
- Develop flow cytometry, flow imaging assays, and explore new technologies and methodology for viral vector characterization and help develop a robust process for vector production.
- Responsible for data analysis using Softmax pro software and graphic display of data using Excel and Power Point presentation formats.
- Demonstrate good verbal communication skills and interpersonal skills to provide insight into the processes used to achieve results of assigned tasks.
- Be able to work in a fast-paced and highly collaborative working environment.
Must have requirements/skills:
- Experience with performing cell culture
- Experience working with biologics (proteins, fusion proteins, mAbs)
- Experience with analytical methods such as ELISA, cell binding assay, or reporter assay
Nice to Have Requirements/skills:
- Experience working with antibody drug conjugate (ADC)
- Experience working with virus generation or virus neutralization assay
- Good presentation and documentation (electronic note book-ELN, testing methods, etc.)
Misc Info:
- Current team: Potency Team focuses on developing bioassays (plate-based and cell-based) for biologic drugs to support manufacturing and clinical studies in early (pre-pivotal), late (pivotal) and commercial stage.
- Our team also develops methods for extended functional characterization of biologic drugs.
- Size of existing team: our team is consisted of ~20 members
Job Types: Full-time, Contract
Pay: $40.00 - $45.00 per hour
Application Question(s):
- How many years of experience do you have performing cell-based and flow cytometry analysis to support biologics? (minimum 3 years)
- How many years of experience do you have working with biologics (proteins, fusion proteins, mAbs)? (minimum 3 years)
- How many years of experience do you have working with analytical methods such as ELISA, and cell binding assay? (minimum 3 years)
- Do you have experience with antibody drug conjugate (ADC)?
Ability to Relocate:
- Oceanside, CA 92056: Relocate before starting work (Required)
Work Location: In person