20 Best Senior Research Scientist jobs (Hiring Now!)

Senior Scientist - Gene-to-Structure
Helix BioStructures LLC. —Indianapolis, IN
The scientist will be expected to improve upon current state-of-the-art methods to accelerate research processes. (not including time as an academic postdoc).
Estimated: $92.1K - $117K a year
Quick Apply
PhD Senior Scientist-Chromatography
BioTechnology Company —Wilmington, DE
As the Chromatography Expert Lead, this role will develop the scientific writing skills of the applications team through generation of data reports, technical…
Estimated: $80.1K - $101K a year
Quick Apply
3d
Postdoctoral/Senior Research Scientist Positions Bioelectricity/Biomagnetism/Biophotonics/cancer
University of Houston —Houston, TX
Experience in cell culture, animal models, microscopy system (fluorescence or phase contrast) for live cell imaging, imaging cell cycle, working with cancer…
$48,432 - $68,942 a year
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Learning Scientist/Engineer
Operations Services, Inc. —Remote
Contributes to the evidence-based design of learning materials, curricula, and enterprise training/education systems; advises on pedagogical processes; designs,…
$95,376.43 - $114,861.93 a year
Quick Apply
6d
Research Scientist
CytoImmune Therapeutics —Toa Baja, PR
Strong experimental skills on in-vitro cell-based functional studies, cell culture and maintenance, and potency assays for studying cell therapy or biological…
From $52,000 a year
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Laboratory Technician
Technology Applications Group, Inc. —Grand Forks, ND
Perform quantitative analysis of production standardized solutions. Perform physical testing and data interpretation on coating specimens using techniques such…
$20 - $24 an hour
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11d
Sr. Scientist
Agile1 - Merck —Cambridge, MA
Work with cross-functional teams including disease area biologists, pharmacologists, and chemists to develop and implement functional assay readouts to validate…
$46.00 - $48.85 an hour
Quick Apply
5d
Lead Graphene Ink Formulation Chemist, Graphene Biosensors
IdentifySensors Biologics Corp —Gainesville, FL
Ph.D. or Master’s degree in Chemistry, Material Science, Chemical Engineering, or a related field. Formulate and develop screen printable graphene inks tailored…
$120,000 - $150,000 a year
Quick Apply
Research Senior Scientist
CytoImmune Therapeutics —Toa Baja, PR
Generate, maintain, and characterize master banks of cell lines used for in vitro studies, including feeder cells, tumor cell lines, and genetically modified…
From $75,000 a year
Quick Apply
Senior Research Scientist
George Washington University —Foggy Bottom, DC
The responsibilities of the Senior Research Scientist will include overseeing study staff, working with the study Principal Investigators and data management…
$97,488.84 - $144,001.59 a year
1d
Senior Research Scientist
Microsoft —Redmond, WA
This includes the ability to influence the design and implementation of conversational AI at Microsoft, and to have impact through publications in the academic…
$117,200 - $229,200 a year
1d
Computational Physicist
Lawrence Berkeley National Laboratory —San Francisco Bay Area, CA
Resolve diverse problems requiring data analysis and evaluation of identifiable factors. This position will contribute to LZ software development, with…
$119,904 - $146,580 a year
12d
Senior Analytical & Research Scientist
Finlays —North Kingstown, RI
Based in our global technical laboratory at the Quonset business park in North Kingstown, Rhode Island, the role also involves working with the US and global…
Estimated: $80.3K - $102K a year
Quick Apply
Senior Research Scientist
QPS, LLC —Newark, DE
In addition to LBA-based immunoassays for PK, biomarkers and immunogenicity assessment, QPS helps develop cell-based assays for neutralizing antibody activity…
Estimated: $80.9K - $102K a year
Quick Apply
4d
Research Scientist II/Senior Scientist I, Biologics Engineering & Assays
Novartis —San Diego, CA
Contribute to analysis and synthesis of results, design of new experiments and clear communication of scientific progress to project team(s); troubleshoot…
$92,800 - $139,200 a year
4d
Senior Research Scientist
Upstart —Remote
Advanced degree in quantitative area of study such as statistics, economics, operations research, finance, mathematics, or related field.
$149,800 - $207,000 a year
2d
Senior Research Scientist [Education & Public Health]
Far Harbor, LLC —Austin, TX
PhD (preferred) in sociology, economics, psychology, public health, or related social science (or Masters with strong experience).
$118,000 - $152,000 a year
Quick Apply
Scientist 3 - Clinical Research
Katalyst Healthcares & Life Sciences Inc —Remote
Responsible for the translation and implementation of (non-medical) scientific concepts into the study design and/or program across planning, execution, and…
Estimated: $93.6K - $119K a year
Quick Apply
4d
Senior Food Scientist
STEVEN CHARLES —Aurora, CO
Provide and communicate technical and business risk assessment and perspective. Support the process design and review on new capability expansion, cost…
$80,000 - $100,000 a year
Quick Apply
2d
Senior Scientist- Metabolic Research
Pfizer —Cambridge, MA
PhD with a minimum of 2 years of post-doc experience in the relevant field. Maintain a awareness of ‘cutting edge’ scientific and technical developments in…
$88,300 - $147,100 a year
9d

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Senior Scientist - Gene-to-Structure

Helix BioStructures LLC. Indianapolis, IN

Quick Apply

Job Details

Full-time Estimated: $92.1K - $117K a year

Benefits

Relocation assistance
Health insurance
Dental insurance
Paid time off
Vision insurance
401(k) matching
Flexible schedule

Qualifications

Protein purification
Biochemistry
Management
Doctoral degree
Data structures
3 years
Project management
Doctor of Philosophy
Biophysics
Data collection
Leadership
Communication skills

Full Job Description

Senior Scientist - Gene-to-Structure

Helix BioStructures, LLC (HBS) is a contract research organization based in Indianapolis, Indiana, providing early drug discovery services to the biopharmaceutical industry. HBS maintains a full suite of services that encompass chemical & structural analysis, protein production, computational modeling, and design. HBS’s core and most popular services are structural biology imaging techniques: X-ray Crystallography and Cryo-EM. HBS was founded in 2018 and has grown considerably. We are looking to add an experienced senior scientist to join our Indianapolis-based team.

Main Responsibilities

This senior-level scientist will support our protein production and structural biology pipelines by producing proteins and setting up crystallization and/or cryo-EM experiments, interfacing with our clients, and writing technical project reports. The scientist will be expected to improve upon current state-of-the-art methods to accelerate research processes. This scientist will also be responsible for managing and supporting the team, planning & tracking all projects to produce and deliver high-quality work to our clients. A proven track record in managing people and projects with a deep understanding of protein construct design, expression, and purification of challenging proteins, biophysical characterization, and structural biology techniques is essential.

Highly desirable hands-on experiences include:

(a) Broad experience in protein production, both expression and purification (mammalian and prokaryotic)

(b) Biochemical, biophysical, and structural characterization of over-expressed and purified proteins.

(d) Cryo-EM grid preparation, data collection, and processing.

(e) Structure building and refinement program usage to phase difficult data sets.

In addition to expertise in crystallography and/or cryo-EM, this scientist will employ a range of experimental strategies (biochemical, biophysical, and/or computational) to support our client’s structure-based drug discovery, antibody discovery, and/or protein engineering. Accordingly, proficiency and a passion for exploring the structural basis of protein-protein and protein-ligand interactions are essential. The successful candidate will be a technical expert who can lead from the bench and collaborate with colleagues on multiple projects in parallel. Overall, you will be an outstanding protein scientist and structural biologist, collaborator, project and people leader who will significantly impact our portfolio with the unique opportunity to help drive discovery projects from inception to early development.

Additional Responsibilities

- Document experimental data and communicate research priorities, progress, and results with clients/project teams.

- Provide the team with project details, priorities, technical and scientific guidance, deliverables, and timelines.

- The candidate will be responsible for managing the team and all projects and providing support for project success.

- This candidate will manage his/her direct reports and provide all the support they need.

- The candidate will be responsible for timely updates on project statuses, reporting to their supervisor informally and to Helix’s customers by formal report writing and oral presentations.

Required Qualifications

- Ph.D. in biochemistry, biophysics, protein engineering, and/or structural biology with experience on multiple challenging protein targets. Productive postdoctoral training and/or industry experience is expected.

- Industry experience: 3-7 years post-Ph.D. (not including time as an academic postdoc).

- Demonstrated competency in protein expression and purification strategies using bacterial, insect, and/or mammalian cell lines.

- Demonstrated knowledge of construct design for structural/biophysical studies and biophysical characterization of proteins.

- Extensive experience in protein X-ray crystallography from protein sample assessment, crystallization, optimization, and data collection to structure determination and refinement.

- Experience with model building and refinement software, such as Phenix, Autoproc, CCP4, Chimera, Rosetta, ShelX, Coot, and Pymol.

- Experience with crystallization robots and standard analytical techniques associated with assessing protein quality during purification.

- Extensive experience reproducing and advanced optimization of crystal hits to produce diffraction-quality crystals.

- Extensive experience with co-crystallization and soaking techniques to help produce ligand-bound protein structures.

- Demonstrated experience and knowledge in people and project management.

- Strong leadership, written and oral communication skills, and attention to detail.

Additional qualifications

- Hands-on experience engineering protein constructs and optimizing the production of protein targets for structural and functional studies.

- Experience in biophysical characterization tools and strategies.

- Ability to generate and characterize milligram quantities of high-quality protein reagents

- Experience with protein engineering and/or design approaches.

- Analysis, design, and/or computational approaches to investigate ligand-protein complexes.

- Experience with Cryo-EM is a plus, especially grid vitrification, screening, and data processing using RELION.

- Lead and provide technical and scientific guidance to the team and manage all projects to produce high-quality results and meet the timeline.

- Excellent communication, interpersonal, organizational, and management skills.

- Fearless attitude to tackle longstanding complex problems.

Location

This position is based in Indianapolis, Indiana, and does offer a hybrid option. Interaction with external service vendors is also expected.

Physical Requirements

Able to lift 30 lb objects.

Able to visualize microscopic objects under microscopes.

Non-standard work schedule, travel, and lab safety

Able to adhere to safe work practices and perform lab work with appropriate personal protective equipment such as but not limited to safety goggles, facial mask, gloves, lab coat/ protective gowning, and closed-toe shoes. Able to work at flexible hours occasionally when performing time-sensitive experiments.

Other job details

- Eligible for Relocation Package

- Competitive Salary + Bonus

- Retirement (matching 401K)

- Health/Dental/Vision Insurance

- Company Apple computer

Helix BioStructures, LLC is an equal opportunity employer, and we embrace the increasingly diverse world around us. Helix BioStructures, LLC prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status, and veteran status.

Job Type: Full-time

Benefits:

401(k) matching
Dental insurance
Health insurance
Paid time off
Relocation assistance
Vision insurance

Experience level:

3 years

Schedule:

8 hour shift

Education:

Doctorate (Preferred)

Experience:

Industry: 3 years (Required)

Ability to Relocate:

Indianapolis, IN 46241: Relocate with an employer provided relocation package (Required)

Work Location: In person

Quick Apply

Senior Research Scientist jobs

Senior Scientist - Gene-to-Structure

PhD Senior Scientist-Chromatography

Postdoctoral/Senior Research Scientist Positions Bioelectricity/Biomagnetism/Biophotonics/cancer

Learning Scientist/Engineer

Research Scientist

Laboratory Technician

Sr. Scientist

Lead Graphene Ink Formulation Chemist, Graphene Biosensors

Research Senior Scientist

Senior Research Scientist

Senior Research Scientist

Computational Physicist

Senior Analytical & Research Scientist

Senior Research Scientist

Research Scientist II/Senior Scientist I, Biologics Engineering & Assays

Senior Research Scientist

Senior Research Scientist [Education & Public Health]

Scientist 3 - Clinical Research

Senior Food Scientist

Senior Scientist- Metabolic Research

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